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IT Infrastructures for Genomic Data Management and Clinical Practice

with Niklas Blomberg, Ph.D., ELIXIR Director, ELIXIR Hub, EMBL-EBI, United Kingdom


An-Dinh Nguyen interviews Niklas Blomberg of ELIXIR on 7 October 2013. Dr. Blomberg will be a keynote speaker during the High-Scale Computing conference at the Clinical Genomics & Informatics Europe Conference & Expo on 4-6 December, in Lisbon, Portugal.

Topics include:

  • Bioinformatics for Managing Large Data Volumes
  • Sustainable IT Infrastructures for Life Science Research and Clinical Practice
  • Advances in IT Infrastructures for Genomic Data Management and Analysis
  • ELIXIR’s Mission, Considerations and Challenges

 


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Public Health Genomics, Data and Ethics

with Anne Cambon-Thomsen, M.D., Director, Research, Centre National de la Recherche Scientifique (CNRS), France


An-Dinh Nguyen interviews Anne Cambon-Thomsen of CNRS on 23 October 2013. Dr. Cambon-Thomsen will be a keynote speaker during the Genome Informatics conference at the Clinical Genomics & Informatics Europe Conference & Expo on 4-6 December, in Lisbon, Portugal.

Topics include:

  • Interdisciplinary Aspects of Public Health Research
  • Ethical, Societal and Legal Issues
  • Applications of Immunogenetics Research
  • Genomic Data Sharing vs. Privacy Protection

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Cloud Computing and Storage for Genomic Research and the Clinic

with Wolfgang Gentzsch, Ph.D., Co-Founder, The UberCloud HPC Experiment; Executive Consultant, HPC, Grid and Cloud; Advisor, EUDAT; Chairman, ISC Cloud Conferences, Germany


An-Dinh Nguyen interviews Wolfgang Gentzsch of The UberCloud HPC Experiment on 4 October 2013. Dr. Gentzsch will be speaking during the High-Scale Computing conference at the Clinical Genomics & Informatics Europe Conference & Expo on 4-6 December, in Lisbon, Portugal.

Topics include:

  • Cloud Computing Services for R&D Scientists and Engineers via UberCloud
  • Progress in Cloud Computing and Storage for Genomic Research and Clinical Practice
  • Challenges: Security, Data Management, Software License Restrictions
  • EUDAT’s Collaborative Data Infrastructure

 


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Genetics and the Public: The Impact of Research

with Heidi Carmen Howard, Ph.D., Assistant Professor, Biomedical Ethics, IQ Healthcare, Radboud University Medical Centre, Netherlands and Senior Research Fellow, Département d’épidémiologie et de Santé Publique, INSERM, Faculté de Médecine, Université Toulouse, France


An-Dinh Nguyen interviews Heidi Carmen Howard of Radboud University Medical Centre and INSERM on 16 October 2013. Dr. Howard will be speaking during the Genome Informatics conference at the Clinical Genomics & Informatics Europe Conference & Expo on 4-6 December, in Lisbon, Portugal.

Topics include:

  • The Translation of Genetic Data into the Clinic
  • The Necessity of Ethical, Social and Legal Considerations in Genomics
  • Genetics for Consumers, Patients and Public Health

 


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Highlights from the Upcoming Clinical Exome Sequencing Conference

with Gholson J. Lyon, M.D., Ph.D., Assistant Professor of Human Genetics, Cold Spring Harbor Laboratory and Research Scientist, Utah Foundation for Biomedical Research, United States


Kip Harry interviews Gholson Lyon of the Cold Spring Harbor Laboratory on 13 September 2013. Dr. Lyon will be speaking during the Clinical Exome Sequencing conference at the Clinical Genomics & Informatics Europe Conference & Expo on 4-6 December, in Lisbon, Portugal.

Topics include:

  • Biology and Targeting of Cancer through Exome Sequencing
  • Technical Steps for Exome Sequencing
  • Analyzing Exome Data
  • Implementing Exome Sequencing in a Clinical Lab
  • Comparing and Contrasting Exome vs. Whole Genome Sequencing
  • Exome Sequencing Survey of Cancers
  • Standardizing Library Prep and Intra-Patient Genomic Heterogeneity
  • Exome Sequencing for Candidate Gene Discovery with Clinical Samples

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The Importance of RNA-Sequencing: Advantages, Applications and Challenges

with David I. Smith, Ph.D., Professor, Department of Laboratory Medicine and Pathology, Mayo Clinic, United States and Melanie Lehman, Ph.D., Research Fellow, Australian Prostate Cancer Research Centre, Queensland University of Technology, Australia


Kip Harry interviews Dr. David Smith from the Mayo Clinic, and Dr. Melanie Lehman from Queensland University of Technology for the upcoming RNA-Seq and Transcriptome Analysis meeting, 5-6 December in Lisbon, Portugal.

Discussion points during the interview include:

  • The advantages of using RNA-Seq for expression analysis over microarrays
  • The impact of RNA-Seq on research and recent advances in the applications of this technology
  • Ways in which RNA-Seq is being utilized clinically
  • Current challenges/limitations with RNA-Seq

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Genetic Analysis of Cancer: Computational and Collaborative Approaches

with Zoltan Szallasi, M.D., Senior Research Scientist, Children’s Hospital Informatics Program, Harvard Medical School, United States and Professor, Systems Biology, Danish Technical University, Denmark


An-Dinh Nguyen interviews Zoltan Szallasi of Harvard Medical School and Danish Technical University on 23 October 2013. Dr. Szallasi will be speaking during the Genome Informatics conference at the Clinical Genomics & Informatics Europe Conference & Expo on 4-6 December, in Lisbon, Portugal.

Topics include:

  • Clinical Validation and Analysis of Cancer Genomic Data
  • Computational and Experimental Methods for Detecting Genomic Instability
  • Quantifying Homologous Recombination in Tumor Biopsies
  • Platinum Sensitivity in Breast Cancer
  • Adapting to Next-Generation Sequencing

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Final Agenda 

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Sequencing

Clinical Exome Sequencing 

RNA-Sequencing 

Informatics

High-Scale Computing 

Genome Informatics 

Pre-Conference Symposia:

Clinical Epigenetics 

Digital Detection 


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